Thank you for choosing the June E. Nylen Cancer Center

We appreciate that you are entrusting your care to our team.


We are the region’s leader in cancer care and blood disorders. Each year, thousands of patients count on us for exceptional care and advanced treatment options. Our team of doctors, nurses, patient advocates, and other professionals are deeply committed to caring for patients with all types of cancer and blood disorders.

We take our role very seriously, providing the highest quality, expert care under one roof. We know that every patient journey – including yours – is unique. From your first visit to survivorship, you will receive personalized, compassionate care. Our team coordinates every step of your health journey, so you can focus on your main goal: getting better.

On behalf of our all of our providers and team members, welcome to the June E. Nylen Cancer Center – the place for hope and healing.  

 
Executive Director Krista McCullough professional headshot

We are privileged to care for you.

Krista McCullough
Executive Director
(712) 252-9372
mcculloughk@jencc.com

 

June Nylen Nursing Photo.jpeg

About our namesake, June E. Nylen

June Eileen (Wiese) Nylen was a registered nurse and caring mother, devoted to helping people in need.

In 1975, June began a valiant five-year fight with lung cancer until she lost her battle on August 7, 1980. Her philosophy to always do what’s right and help others where and whenever possible inspired the Nylen family including her children.

Putting his mother’s philosophy into action, June’s son Mark made a generous gift in his mom’s memory to purchase a new Linear Accelerator for the cancer center. In December 2004, the Siouxland Regional Cancer Center officially changed its name to the June E. Nylen Cancer Center in honor of June’s courageous cancer fight and her goal to better life for others.


Our Mission

To provide the highest quality, compassionate care through prevention, treatment, and research.

Our Vision

Be the region’s preferred choice for hope and healing.

The Principles That Guide Our Organization

PEOPLE – Our physicians and staff are the difference-makers to each patient. It is important that we support and invest in our employees so they can give their best to our patients. We will treat each other with courtesy and respect at all times, no matter what. 

SERVICE – We don’t just treat cancer; we treat people and we believe it’s purposeful and a privilege. Through coordinated teamwork, we personalize the care of patients and treat each other with dignity to ensure the best experience possible.

QUALITY – We pursue safety and excellence in order to improve outcomes for our patients by creating an environment which supports collaboration, mutual trust, and authentic communication.

COST – We will follow best practices to ensure financial health in order to continue to expand our services and support our community.

GROWTH – We will act with purpose, focused on results and creating value. We will build strong relationships with our referring physicians. We will continue to advance cancer and hematology services in order to provide comprehensive diagnosis, treatment, follow up, education and prevention to our patients.

COMMUNITY – We value the support of the community and are stewards of this generosity. We are advocates to reduce the impact of cancer in our region by striving to provide education, prevention, and early detection initiatives to our service area.


Our history

Expert cancer care close to home became a reality when we opened our doors on March 27, 1995 as the Siouxland Regional Cancer Center through a collaborative partnership between UnityPoint Health – St. Luke’s and MercyOne Siouxland Medical Center under a parent organization called Health, Inc. The Board of Directors was comprised of executive officers from both organizations, as well as community members. In December 2004, the name was changed to the June E. Nylen Cancer Center following a generous gift from Mark Nylen in memory of his mother. Upon the acquisition of MercyOne Siouxland Medical Center by UnityPoint Health on September 1, 2025, the June E. Nylen Cancer Center became a service of UnityPoint Health – Sioux City.

Under the leadership of our first medical director and hematology and oncology pioneer, Dr. John “Jack” Michalak, we made history as the region’s first dedicated center for cancer care and blood disorders. Throughout the years, we have continued to bring the latest in cancer and blood disorder prevention, diagnosis, and treatment to Siouxland, including 3D radiology, PET or Positron Emission Tomography, stereotactic radiosurgery, and radiation therapy. Our commitment of ensuring cutting-edge technology is not alone, as our goal is ultimately to improve outcomes for our patients.

The advancements have been made possible because of support from the Siouxland community and generous donors who realized the importance of providing exceptional cancer and blood disorder care in Sioux City, Iowa.  Since our doors first opened, our name, technology, treatment, and approach to care has evolved, but our reputation remains the same as it did on the first day.

Today, our team of doctors, nurses, and other professionals at June E. Nylen Cancer Center works together to care for patients from diagnosis through survivorship. As we celebrate 30 years as the area’s leader in advanced treatment options, we are privileged to be the place patients from across the region choose for expert care as well as hope and healing close to home. 

An exterior photo of the cancer center at sundown